Applications
LIFE SCIENCES, BIOTECH, PHARMA
Filtration solutions are critical for many life sciences applications, ranging from biotech, extracts, pharmaceutical production to research and development. In order to achieve optimal results, it is important to choose the right filtration technology for your specific application. Depth filtration is useful for removing contaminants from liquids, including particles, bacteria, and viruses. By choosing the right filtration technology for your biotech, pharma or other life sciences application, you can achieve optimal results and ensure the quality and purity of your final product. Our customized solutions range from standard depth filtration and cake filtration systems, to singe-use solutions for the highest requirement.
CANNABIS OIL
There are several ways to extract the CBD rich oil for therapeutic use from the dried and heated buds. The most common extraction methods are ethanol and CO2 extraction. While these methods are effective in extracting the CBD, they often leave behind unwanted materials such as plant waxes, lipids, and chlorophyll. Filtration is an important process that helps to remove impurities and unwanted materials from the oil. Find out more ...
BIOLOGICS
Cell broths are commonly used in bioprocessing and biopharmaceutical production to extract target molecules from cells, such as proteins, enzymes, and antibodies. However, cell broths can also contain unwanted materials such as cell debris, nucleic acids, and lipids, which can negatively impact downstream processes and the quality of the final product. We have a lot of experience in clarification of cell broths with very high cell densities. Our BIO SD product line has been developed to handle these challenges in a fully disposable single use design.
MAMMALIAN CELLS AND MAB's
Clarification of mammalian cells is a critical step in bioprocessing and biopharmaceutical production to ensure the purity and quality of the final product. The ongoing optimization of mammalian cell lines and fermentation processes leads to higher cell densities/titers and higher monoclonal antibody (mAb) yields. Due to this optimization also the biomass increases, including cell debris and other impurities, which challenges the clarification/harvest step.
BLOOD PLASMA
Depth filtration is a widely used method in the blood plasma fractionation process to purify and separate different protein components in plasma. Blood plasma is composed of various proteins, including immunoglobulins, albumin, and clotting factors, among others, which have different molecular sizes and physical properties. Depth filtration is an effective method for blood plasma fractionation and can be used in combination with other separation techniques to achieve the desired level of purity and separation of protein components. It is an important step in the production of many plasma-derived therapeutics used to treat a range of medical conditions.
PLASMID DNA
The main advantage of alluvial filtration for the clarification step is the elimination of the two-step approach. Due to the increased filtration capacity the traditional approaches such as centrifugation followed by depth filtration or a two-step depth filtration are not necessary anymore. The simultaneous reduction of impurities e. g. HCP is another advantage
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FLAVORS & FRAGRANCES
Flavors and fragrances are complex mixtures of various components that provide the desired taste or scent in food, beverages, and personal care products. Filtration is a crucial step in the production of flavors and fragrances to ensure the final product meets the necessary quality and safety standards. The appropriate filter type should be chosen based on the properties of the flavor or fragrance and the level of impurities present. We are already selling to many flavors and fragrances manufacturing sites all over the world and therefore have a lot of experience in this particular application area.
ACTIVE PHARMACEUTICAL INGREDIENTS (APIs)
During the manufacturing process of APIs, various impurities such as particles, metals, and residual solvents may be present, which can impact the safety and efficacy of the final product. Filtration is a common method used to remove these impurities and achieve the desired level of purity. The choice of depth filter will depend on the properties of the API, the level of impurities, and the desired level of filtration. Our product portfolio, especially the media with immobilized activated carbon, offers a lot of potential for API manufactures around the world to optimize their process.
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COSMETICS
Active ingredients are the main components in cosmetics that provide the desired therapeutic or aesthetic effects, such as anti-aging, hydration, or skin brightening. Filtration is a crucial step in the production of cosmetic products to remove any impurities and ensure the active ingredients meet quality and safety standards. Active ingredients for the cosmetic industry or bulk ingredients for your formulation – we know the best fitting technology to clarify and final filter your product. As a global leader in the filtration of cosmetics we can offer you the right product.
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NATURAL EXTRACTS
Natural extracts are complex mixtures of various components derived from plants, animals, or microorganisms that provide a range of health benefits or are used as flavoring or coloring agents. Whatever you would like to extract from a natural source like herbs, flowers, plants or fruits, depth filtration still is the most efficient way offering the filtration capacity you need to run your process economically. Our products fulfill all the requirements for cosmetics as well as for pharmaceutical GMP production processes.
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